Albumin/Globulin (A/G) Ratio Calculator
Estimate your A/G Ratio and Globulin levels instantly using this professional medical utility. Enter your Total Protein and Albumin results from a comprehensive metabolic panel (CMP) or liver function test. The calculator provides immediate diagnostic classifications, spectrum visualizers, and detailed descriptions of liver, kidney, or immune system implications.
A/G Ratio Calculator
A/G Ratio
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Ratio
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Globulin (Calculated)
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g/dL
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A/G Ratio Spectrum
Scale: 0.5 - 3.0+
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Understanding the A/G Ratio & Globulin
Your blood contains two major families of proteins: albumin and globulins. Measuring their proportions helps detect physiological abnormalities:
- Albumin: Produced exclusively by the liver, albumin acts as a transport molecule and maintains osmotic pressure, keeping fluid from leaking out of blood vessels. It makes up roughly 60% of total serum protein.
- Globulins: A group of proteins produced partly by the liver and partly by the immune system. They include immunoglobulins (antibodies), enzymes, and transport proteins.
- A/G Ratio: Calculated by dividing Albumin by Globulin. It describes the numeric balance between these two protein classes.
Interpreting Abnormal Results
An A/G ratio outside the typical reference range (generally 1.1 to 2.5) may point to distinct clinical conditions:
- Low A/G Ratio (< 1.1): Usually caused by low albumin levels or high globulins. This occurs in liver cirrhosis, nephrotic syndrome (kidney protein leakage), inflammatory diseases, autoimmune disorders, or hematological malignancies.
- High A/G Ratio (> 2.5): Less common, often triggered by severe dehydration (which raises serum albumin concentration) or low immunoglobulins (hypogammaglobulinemia) due to immune system disorders.
Medical Disclaimer: This online calculator is for informational purposes only and is not a substitute for professional medical advice, diagnosis, or laboratory blood tests. Always consult a qualified healthcare provider to interpret your comprehensive metabolic panel (CMP) results and establish a treatment plan.
